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Symbyax Drug Interactions

Mexiletine
Taking Symbyax with mexiletine can raise the amount of Symbyax in your blood, which may increase your risk of side effects. If you are taking these drugs together, your healthcare provider may need to adjust your doses of them.
 
Miscellaneous Antidepressants
Combining Symbyax with antidepressants may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome, as it can be very dangerous.
  
Monoamine Oxidase Inhibitors
If Symbyax and an MAOI are taken together, it can cause life-threatening side effects. Never take an MAOI and Symbyax at the same time, and do not take Symbyax if you have taken an MAOI within the past 14 days. Also, because Symbyax stays in your system for so long, do not take an MAOI if you have taken Symbyax within the past five weeks.
 
Nonsteroidal Anti-Inflammatory Drugs
Taking Symbyax and NSAIDs together can increase your risk of stomach bleeding. Talk to your healthcare provider before combining these two medications.
 
Norfloxacin
Combining Symbyax with norfloxacin can raise the amount of Symbyax in your blood, increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to adjust your doses of them to prevent drug interactions from occurring.
 
Ofloxacin
Taking Symbyax with ofloxacin can raise the amount of Symbyax in your blood, potentially increasing your risk of side effects. If you are taking these drugs together, your healthcare provider may need to adjust your doses of them to avoid drug interactions.
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Symbyax Drug Information

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