Drug Interactions With Risperidone (Cont.)

 
Certain Anticonvulsants
Taking risperidone with certain anticonvulsants (seizure medications) can decrease the level of risperidone in your blood, perhaps making it less effective. Your healthcare provider may need to increase your risperidone dosage.
 
Cimetidine (Tagamet)
Taking risperidone with cimetidine can increase the level of risperidone in your blood, increasing your risk of risperidone side effects. Your healthcare provider may need to decrease your dose of risperidone.
 
Clozapine (Clozaril, FazaClo)
Taking risperidone with clozapine can increase the level of risperidone in your blood, increasing your risk of risperidone side effects. Your healthcare provider may need to decrease your dose of risperidone.
 
Fluoxetine (Prozac, Symbyax)
Taking risperidone with fluoxetine can increase the level of risperidone in your blood, increasing your risk of risperidone side effects. Your healthcare provider may need to decrease your dose of risperidone.
 
Paroxetine (Paxil, Paxil CR)
Taking risperidone with paroxetine can increase the level of risperidone in your blood, increasing your risk of risperidone side effects. Your healthcare provider may need to decrease your dose of risperidone.
 
Ranitidine (Zantac)
Taking risperidone with ranitidine can increase the level of risperidone in your blood, increasing your risk of risperidone side effects. Your healthcare provider may need to decrease your dose of risperidone.
 
Rifamycin Antibiotics
Taking risperidone with rifamycin antibiotics can decrease the level of risperidone in your blood, perhaps making it less effective. Your healthcare provider may need to increase your risperidone dosage.
 
(Drug Interactions With Risperidone Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;