Drug Interactions With Olanzapine

A few of the drugs that can potentially interact with olanzapine include alcohol, carbamazepine, and ketoconazole. Drug interactions with olanzapine can increase your risk of side effects or perhaps make olanzapine less effective, among other things. You should make sure to talk with your pharmacist or healthcare provider about the olanzapine drug interactions that may apply to you.
 

Olanzapine Drug Interactions: An Introduction

Olanzapine (Zyprexa®) can potentially interact with a number of other medicines. Some of these medicines that may lead to olanzapine interactions include:
 

Olanzapine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when olanzapine is combined with any of the drugs listed above.
 
Alcohol
It is not recommended that you drink alcohol while taking olanzapine. Taking alcohol and olanzapine together may cause unwanted side effects (see Alcohol and Zyprexa).
 
Carbamazepine (Epitol, Equetro, Tegretol, Tegretol XR)
Taking olanzapine with carbamazepine can decrease the amount of olanzapine in your blood, perhaps lowering its effectiveness. If you are taking these drugs together, your healthcare provider may need to increase your dose of olanzapine.
(Drug Interactions With Olanzapine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;