Lithium (Eskalith^®, Eskalith CR^®, Lithobid^®) is a prescription medication licensed for treating bipolar disorder. It comes in several different forms and strengths; lithium capsules are available in three strengths, tablets are available in one strength, and the syrup is available in one strength. There are also two strengths available for extended-release lithium: 450 mg and 300 mg tablets.

The recommended starting lithium dose for acute mania is 600 mg three times daily (for immediate-release tablets, capsules, or syrup). You can also take two lithium 450 mg extended-release tablets or three 300 mg extended-release tablets twice a day (for a total of lithium 900 mg twice daily). Extended-release lithium tablets should not be chewed, crushed, or broken; they should be swallowed whole.

(Click Lithium Dosage for lithium dosing guidelines for the long-term maintenance treatment of bipolar disorder and to find out what factors your healthcare provider will consider before making a dosing recommendation for your particular situation.)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD

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