Lamotrigine Side Effects (Cont.)

Serious Lamotrigine Side Effects

Some side effects of lamotrigine, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
 
 
  • Any unusual bruising or bleeding
 
  • Signs of liver damage, such as yellow eyes or skin (jaundice)
 
  • Severe muscle pain
 
  • Frequent infections
 
  • Signs of a dangerous allergic reaction, including:
o Hives or any rash
o Fever
o Swollen lymph nodes (swollen "glands")
o Painful sores in or around the mouth or eyes
o Swelling of the lips or tongue
 
Lamotrigine can cause very serious skin rashes and allergic reactions. These rashes can cause large sections of the skin to die and can cause disfigurement or even loss of life. (see Lamictal Rash.)
 

Rare Lamotrigine Side Effects

Rare side effects of lamotrigine occurred in less than 5 percent of people taking the drug. Because these side effects are less common, it can be difficult to tell whether they are actually caused by lamotrigine or by other factors unrelated to the medication.
 
Some of these side effects include but are not limited to:
 
  • Vaginal infection or irritation
  • Speech problems
  • Bladder infection (urinary tract infection or UTI)
  • Concentration problems
  • Joint pain
  • Loss of appetite
  • Neck pain
  • Sinus infection
  • Sensitivity to the sun
  • Nervousness
  • A spinning sensation (vertigo)
  • Memory loss (amnesia)
  • Increased sex drive
  • Bloody nose
  • Dry skin
  • Sweating
  • Migraine headaches
  • Weight gain (see Lamictal and Weight Gain).
     
(Lamotrigine Side Effects Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;