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Lamotrigine Dosing

General Information on Dosing With Lamotrigine

Considerations for people taking lamotrigine include the following:
  • Lamotrigine comes in regular tablets, orally disintegrating tablets, and lamotrigine CD tablets. It is taken by mouth, usually once or twice a day.
  • Lamotrigine CD tablets are "chewable dispersible" tablets. These tablets can be swallowed whole, chewed, or "dispersed" in a small amount of liquid. To disperse lamotrigine CD tablets, add the tablet to a small amount of liquid, about a teaspoonful or enough to cover the tablet. Wait a minute, then swirl the liquid to make sure the tablet is broken down, and take by mouth immediately.

Do not attempt to take a partial dose of lamotrigine CD tablets by cutting them in half or taking half of the dispersed tablet in liquid.

  • The orally disintegrating tablets should be placed on the tongue and moved around in the mouth. They will dissolve rapidly. They can be swallowed with or without water.


  • Regular lamotrigine tablets can be broken in half if necessary to obtain the proper dosage. However, these tablets can be particularly difficult to break. You may want to consider purchasing a "pill splitter" or ask your pharmacist to split them for you.
  • The medication can be taken with or without food. If lamotrigine upsets your stomach, try taking it with food.
  • Lamotrigine should be taken at the same time(s) each day to maintain an even level in your blood.
  • For the medication to work properly, it must be taken as prescribed. Lamotrigine will not work if you stop taking it.
If you are unsure about anything related to lamotrigine or lamotrigine dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without discussing it with your healthcare provider (see Lamictal Withdrawal).
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