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Depakote Safety

There are many steps you can take to help ensure the safety of Depakote® (divalproex sodium) use. Being aware of the potential side effects of this drug can help you be prepared if they do occur and to know if they are life-threatening.
 
The most common side effects that were reported with Depakote during clinical studies included vomiting, drowsiness, nausea, headaches, and shakiness. These side effects are often minor and, in most cases, either do not require medical attention or can be treated easily by you or your healthcare provider.
 
You may not be able to take Depakote safely if you have certain other medical conditions. Talk to your healthcare provider before using this particular drug if you have:
 
  • Liver disease, such as liver failure or cirrhosis
  • A urea cycle disorder
  • Mental retardation
  • A blood disorder
  • Any allergies, including allergies to food, dyes, or preservatives.
  •  
(Click Depakote Side Effects and Depakote Warnings and Precautions for more information about Depakote safety, including a more complete list of potential side effects of the medication and warnings on who should avoid this drug.)
 
Know the Signs - Concussion Safety
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