Drug Interactions With Asenapine
Some medications can react negatively with asenapine, leading to potentially serious drug interactions. If asenapine is combined with blood pressure medications or CYP1A2 inhibitor medications, it could cause life-threatening problems, such as a dangerous change in the heart's rhythm or extremely low blood pressure. To avoid such reactions, it is important to tell your healthcare provider about any other medicines you are taking.
An Overview of Asenapine InteractionsAsenapine (Saphris®) can potentially interact with several other medications. Some of the medicines that may lead to drug interactions with asenapine include:
- Alcohol or other substances or medications that cause drowsiness
- Blood pressure medications
- CYP1A2 inhibitor medications, such as:
- Medicines that cause a certain change in the heart rhythm known as QT prolongation (see QT-Prolonging Medications for a list of such drugs).