Abilify

Abilify is a prescription drug licensed for the treatment of bipolar disorder, schizophrenia, and major depression (when used with antidepressants). Although it is not a cure for these conditions, it can control symptoms and help keep them from returning. Abilify tablets come in a number of strengths and are generally taken once a day. Side effects of Abilify can include nausea, insomnia, headaches, and anxiety.

 

What Is Abilify?

Abilify® (aripiprazole) is a prescription medication that is used to treat schizophrenia and bipolar disorder. It is also approved to be used along with antidepressants for the treatment of major depression (this is known as "augmentation").
 

Who Makes Abilify?

Abilify is manufactured by Otsuka America Pharmaceutical, Inc. and Bristol-Myers Squibb Company.
 
(Click Abilify Uses for more information on what Abilify is used for, including possible off-label uses.)
 

How Does Abilify Work?

Abilify belongs to a group of medications called atypical (or second-generation) antipsychotic medications. It is not entirely clear how Abilify works for the treatment of schizophrenia, bipolar disorder, or major depression. However, it is known that the drug blocks or lessens the effects of several chemicals in the brain. These brain chemicals (such as dopamine and serotonin) may be elevated in people with schizophrenia or bipolar disorder (also known as manic depression).
 
Abilify is not a cure for bipolar disorder, schizophrenia, or major depression. It only helps to control symptoms (see Symptoms of Depression, Symptoms of Schizophrenia or Bipolar Disorder Symptoms).
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;